Metformin can prevent obesity in type 2 diabetes.
Recently (in 1994), Metformin was launched in the USA. Sometimes Metformin referred to as oral insulin, but it is not true. Actually, Metformin is successfully used in the treatment of type 2 diabetes, but it is not an insulin substitute. By action Metformin is significantly weaker than insulin, however it is characterized by unique effect. Simultaneous use of Metforminand insulin helps to avoid fat deposits under the skin at daily insulinization. So, if buy Metformin weight loss can be achieved easier. Besides, Metformin lowers the glucose level in the blood. Metformin shows the pharmacological activity only under insulin in the blood and doesn't reduce carbohydrates concentration in the blood plasma.At simultaneous application of insulin with Metformin, the patient can control his own disease and body weight.
Metformin use in the treatment of type 2 diabetes.
Metformin is an oral drug to be used in a combination with insulin injections only. Metformin increases insulin receptors sensitivity, reducing insulin influence on subcutaneous fat deposits.
Metformin use with androgens provides significant fat burning.
The therapy with Metformin usually does not exceed 21 days because Metformin fails to burn fat deposits if used longer. The patient's organism adapts to active Metformin components, therefore 30-40 day gap is recommended before the second course of therapy.
Metformin dosage in the treatment of type 2 diabetes.
To start the treatment is better from minimum daily Metformin dose. Buy Metformin 850 mg cheap, at this dose possible side-effects are minimal. If an organism tolerates the drug well, a dose can be increased to an average daily dose of 2000mg.
The daily dose of Metformin is to be taken once a day, orally, during or after dinner. Sometimes it is reasonably to divide a daily dose into two equal parts and take twice a day, in the morning and in the evening during or after a meal.
The maximum daily safe Metformin dose is 2500mg.
Possible side-effects of Metformin.
If a dose is selected incorrectly or in allergic reaction to active drug components certain side-effects can be observed.
The most frequent side-effects are experienced in the gastrointestinal tract: nausea, vomiting, stomach ache, appetite loss can be observed and bitter taste in the mouth as well.
These effects are typical during the first several days of drug application. In most cases they pass without any complications, but if the patient feels badly, urgently visit the doctor for consultation.
Very seldom, the drug use may lead to B12 vitamin production disturbed, difficult breathing, weakness and excessive sleepiness.
To avoid adverse negative effects for an organism, start using the drug from the minimum dose and follow recommendation on duration of the treatment course.
Combination of Metformin and other medications.
A normal application of Metformin is combined with insulin.
At long-term Metformin application the drugs regulating protein metabolism in an organism are recommended because long-term Metformin application decreases the glycogen level in an organism.
Metformin is not recommended to be used simultaneously with Triiodothyronine and Oxymetholone. These drugs significantly reduce tolerance to glucose and hyperglycemia is possible.
The form of Metformin.
Metformin 500 mg, Metformin 850 mg, and Metformin 1000 mg are supplied in tablets for oral administration.
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